White Paper
The New Weight Loss Pill: What You Need to Know
White Paper Summary
In December 2025, the FDA approved a new oral tablet formulation of Wegovy® (semaglutide), marking the first available GLP-1 drug for the treatment of obesity in an oral formulation.
Like GLP-1 injections, the new oral version is indicated in combination with a reduced calorie diet and increased physical activity to reduce excess body weight. Additionally, the tablets are approved to reduce the risk of major adverse cardiovascular events in adults with established cardiovascular disease who are either obese or overweight.
The new tablet formulation will be available in dosages of 1.5 mg, 4 mg, 9 mg, and 25 mg. Due to differences in how the body breaks down the oral version versus an injection, the pill comes in a higher dose than the injection and must be taken daily rather than weekly.
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